Log Feb21, 2025: Mini bioinformatics project(0). Bumpy start

Before I start all bioinformatics projects in class, before I meet up with a professor, I want to actually experience little bit of bioinformatics.


So, with ChatGPT, I tried to build a mini project.

I picked a familiar topic: RNA expression of sickle cell anemia. >> I changed my mind


But even before I got to download the dataset...

While downloading the necessary packages, I ran into a tedious situation.

I was trying to download "STAR," but conda couldn't find that package in the bioconda channel—even though the Anaconda site says it's available there.


Long story short, I had to mess with my .zshrc file several times, and I ended up downloading STAR by cloning the GitHub repository and running the makefile myself.

It's been a while... I even started thinking about the concept of a makefile.

And worse, I had to modify the makefile (because I'm using an M2 MacBook).


At that point (after 2 hours?), I got a strong feeling that something was very wrong from the beginning.

So I asked ChatGPT and Googled...

My conclusion is that I don't really need a fancy M2 MacBook Pro for bioinformatics.

I'm gonna work on Linux anyway (probably on the cloud... or on a physical laptop—I actually have one).

So... yeah, I will try on Linux!

I highly recommend using a Linux environment for bioinformatics—for your mental health!



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